SELE and urticaria: In most cases, FEX significantly decreased the expression of Intercellular Adhesion Molecule-1 (ICAM-1) and Endothelial Leukocyte Adhesion Molecule-1 (ELAM-1) on endothelial cells (p < 0.05), decreased the expression of tryptase and some adhesion molecules in urticaria sufferers.27