Although heterozygous FANCA gene mutation does not definitively cause FA, it may cause ovarian insufficiency in women and thus affect their reproductive ability.[8] Additionally, heterozygous mutations in the FANCA gene increase cancer susceptibility in a sporadic manner, which is associated with a variety of tumor diseases such as gastric cancer, prostate cancer, and colorectal cancer.[9]. The gene discussed is FANCA; the disease is Familial prostate cancer.