The tumor-initiating cell frequency we observe in MDA-MB-468 tumors (Fig. 7C, left) reflects CD24−CD44+ cell percentages (Fig. 7B, left) and tumor growth (Fig. 7A, left) data, and provides a probable explanation for why MDA-MB-468 cells, ALDH1A3 knockdown results in increased tumor growth [29]. This evidence concerns the gene ALDH1A3 and neoplasm.