β-catenin was not degraded by loss of NF2 in meningioma cells (Supplementary Fig. 5b), and subcellular fractionation of meningioma cells after doxycycline-inducible Merlin rescue showed β-catenin was distributed across the plasma membrane, cytoplasm, cytoskeleton, and nucleus with MerlinL46R and MerlinA211D rescue, but was only enriched at the plasma membrane and in the nucleus with MerlinWT rescue (Fig. 2d). Here, NF2 is linked to meningioma.