DNA methylation profiling controlled for artifacts from copy number variants (CNVs) reveals meningiomas are comprised of Merlin-intact, Immune-enriched, and Hypermitotic DNA methylation groups7, which are concordant with groups and subgroups of meningiomas derived from RNA sequencing or DNA methylation profiling integrated with RNA sequencing, CNVs, and SSVs8,11,12. Here, NF2 is linked to meningioma.