Rescue of MerlinS13D but not MerlinS13A sequestered β-catenin at the plasma membrane in meningioma cells without causing dramatic differences in the subcellular localization of Merlin itself (Fig. 2d), and MerlinS13A but not MerlinS13D rescued Wnt signaling in meningioma cells lacking NF2 (Fig. 3e and Supplementary Fig. 6c). The gene discussed is NF2; the disease is meningioma.