Overall, the most commonly mutated genes among all iCCA patients were TP53 (21%), IDH1 (20%), BAP1 (17%), ARID1A (16%), FGFR2 (16%), CDKN2A (14%), CDKN2B (12%), KRAS (12%), and PBRM1 (12%). Here, CDKN2B is linked to infantile convulsions and choreoathetosis.