Additionally, a de novo single nucleotide variation in ADNP2 has been associated with developmental abnormalities (Chung et al. 2015), and CpG hypermethylation of ADNP2 has been linked with post-traumatic stress disorder (PTSD) (Bainomugisa et al. 2021). Here, ADNP2 is linked to post-traumatic stress disorder.