In accordance with this, women with FGS (defined as presence of sandy patches on colposcopy exam) were found to have increased expression of the HIV entry molecule CCR5 on both systemic circulating and local cervical CD4+ T cells and CD14+ monocytes, which decreased on both cell populations post-PZQ treatment in both compartments [107]. The gene discussed is CCR5; the disease is focal segmental glomerulosclerosis.