To delineate the clinicopathological characteristic of NELL1-positive MGN, we compared 22 NELL1 single-positive MGN cases with 60 PLA2R1 single-positive MGN cases and 42 Negative cases, excluding all lupus nephritis cases (n = 17); THSD7A single-positive MGN cases were excluded from the comparison because of the small number of cases (n = 2) (Fig. 2). The gene discussed is PLA2R1; the disease is idiopathic membranous glomerulonephritis.