Recently, a pioneering study has demonstrated that Aspirin has partial inhibitory effect on Hpa,16 a feature that may be held responsible, in part, for the anti‐inflammatory effects of NSAIDs, including in AP17, 18 Another compound that possesses a potential pancreato‐protective effect against AP is Trehalose, a naturally occurring non‐reducing disaccharide.19 The gene discussed is HPSE; the disease is alkaline phosphatase measurement.