In low‐grade gliomas, expression level of METTL16 had a negative correlation with that of CD8+ T lymphocytes (r = −0.17, p = 0.025, Figure 13A), and that of NFE2L2 had a positive correlation with M2 macrophages (r = 0.24, p = 0.0019, Figure 13B), neutrophils (r = 0.19, p = 0.011, Figure 13C) and activated memory CD4+ T cells (r = 0.22, p = 0.0034, Figure 13D). The gene discussed is METTL16; the disease is central nervous system cancer.