In the FGF10 feeding group, the percentage of organoids positive for ESG markers K7 and NKA rise up to 8.33±2.31% and 2.03±0.61%, respectively; meanwhile, the positive percentage of organoids for HF markers K27 (30.38±4.06%) and K73 (77.85±13.56%) increased slightly, but there was no significant difference compared with the NC group (Figure 3E, 3F). The gene discussed is KRT73; the disease is hydrops fetalis.