SLC16A1 and hepatocellular carcinoma: On the contrary, incubation with exosomes derived from SLC16A1-AS1 knockdown HCC cells could not induce SLC16A1 upregulation and M2 polarization in macrophages, while it was distinctly rescued by overexpression with SLC16A1 (Fig. 3H and Supplementary Fig. S3F).