CCAR1 and glioblastoma: Similarly, the invasion ability of U87MG and U251MG cells in shPDIA5-1+LV-CCAR1 and shPDIA5-2+LV-CCAR1 GBM cells was significantly improved compared to shPDIA5-1 and shPDIA5-2 GBM cells (Figure 6C-D).