KDM1A and non-small cell lung carcinoma: Additionally, Sun et al. (2011) showed that the nuclear receptor TLX inhibits miR-137 expression by recruiting histone lysine-specific demethylase 1 (LSD1) to the miR-137 genomic region and that LSD1 is also a downstream target of miR-137 in NSCLC, where its expression is negatively correlated with that of miR-137 (Zhang et al., 2017), suggesting that miR-137 and LSD1 to form a feedback regulatory loop.