It has been shown that exosome‐derived lncRNA RPPH1 can act on β‐III microtubule proteins and exert an inhibitory effect on their ubiquitination, which can induce the production of EMT in colorectal cancer (CRC) cells, and consequently, participate in the process of CRC progression and metastasis in vivo.43 Here, RPPH1 is linked to colorectal carcinoma.