Using intraductally injected xenografts, Kozma KJ et al. reported high LOXL1 expression in ILC breast tumour cells, and they demonstrated that LOXL1 gene knockdown and treatment with the β-aminopropionitrile (BAPN) pan-LOX inhibitor impairs the growth of breast lobule xenograft tumours, reducing tumour cell proliferation and altering collagen fibre tissue 51. This evidence concerns the gene LOXL1 and breast neoplasm.