MMP12 and neoplasm: To elucidate the mechanism of MMP regulation in diverse cell types in CC, we identified DEGs in individuals between MMPs high-expression and low-expression groups, finally it was found MMP-1, MMP-12, MMP-13 and MMP-7 were upregulated, but MMP-14, MMP-19, MMP-2, and MMP-21 were downregulated in diverse cell types (Figure 1D), suggesting biochemically redundant members of the MMP family may have intricate interplay in tumor progression.