SUSD2 and urinary bladder cancer: Analysis of cell cycle phases revealed a significant decrease in the G0/G1 phase population and a significant increase in the sub-G1, S and G2/M phase population in BFTC-905 cells with SUSD2 knockdown, indicating that SUSD2 silencing inhibited bladder cancer cell growth by disrupting cell cycle progression and inducing cell apoptosis (Figure 4A and 4B).