In the HPA database, we searched the expression of the two genes in the head and neck tumor cell lines, and found that the cell lines with high expression of ALDOA were PE/CA-PJ49, the cell lines with high expression of VEGFA were SNU-1214 (Supplementary Figure 2), ALDOA were highly expressed in OSCC lines, and VEGFA were highly expressed in laryngeal squamous cell lines. Here, ALDOA is linked to head and neck neoplasm.