To identify genes related to ferroptosis, we utilized the GeneCard databases (https://www.genecards.org/) to search “ferroptosis” as the keyword and downloaded the list of the ferroptosis-associated genes (FAGs), and ACSL4 (Log2FC = 1.178; p.adj = 0.034) and MIR626 (Log2FC = −1.184; p.adj = 0.034) might be FAGs in the progression of CD (Figure 1b). This evidence concerns the gene ACSL4 and Cowden disease.