In contrast, 244 genes (227 unique for this infection) were differentially expressed after infection with swH1N1 compared to control (Supplementary Table S5) and included a substantial number of ISGs (HERC5, HERC6, IFIT2, IFIT3, IFIT5, IFITM1, ISG20, OAS2, OASL, and USP18). This evidence concerns the gene HERC6 and infection.