Thrombocytopenia occurs in approximately 10-50% of patients with HIV as one of the first clinical signs of infection [1]. A study of 1004 HIV-infected patients showed that thrombocytopenia was more common in white males and older subjects, as well as in patients with acquired immunodeficiency syndrome (AIDS), CD4 cell numbers <200/mm3, and advanced disease [2]. This evidence concerns the gene CD4 and Thrombocytopenia.