CRF: chronic renal failure; DM: diabetes mellitus; ESRD: end-stage renal disease; GIT: gastrointestinal tract; HD: hemodialysis; INR: international normalized ratio; KT/V: K is the urea clearance (mL per minute), T is the treatment duration (minutes), and V is the volume of urea distribution (mL); NSAIDS: non-steroidal anti-inflammatory drugs; PD: peritoneal dialysis; PTH: parathyroid hormone. This evidence concerns the gene PTH and chronic kidney disease.