While the presence of bone metastasis at recurrence is reported as a poor prognostic factor in terms of both the PFS and OS in patients with advanced EGFR‐positive NSCLC [18], no reports are available on the prognostic impact of bone metastasis in EGFR‐positive NSCLC patients with PR. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.