Fre P has shown the highest cell viability inhibition in human OVCAR4 ovarian cancer cells supplemented or not with vitamin D, followed by Egy P, and then, Ger P. This finding may be because the Fre P is the only type that contains artepillin C and caffeic acid which are among the major anti-cancer ingredients of propolis. This evidence concerns the gene FRZB and ovarian cancer.