PRDX3 and acute myeloid leukemia: In HFD-induced mice hepatocytes and PA-induced AML-12 cells, the researchers found that carnosol (CAR) treatment can maintain mitochondrial membrane potential and inhibit mitochondrial oxidative stress by specifically interacting with and upregulating the expression of the peroxiredoxin 3 (PRDX3), a mitochondrial H2O2 scavenger.