In hypoxic conditions, TGF‐β signalling upregulates RBFOX2 in BrC cells (MCF‐7 and HCC‐1806), thereby inhibiting ESRP1 at the transcriptional level, consequently fostering the pro‐metastatic MENAΔ11a subtype, enhancing epithelial‒mesenchymal transition (EMT) in BrC cells, and augmenting invasiveness.101. Here, RBFOX2 is linked to hepatocellular carcinoma.