In agreement with the findings of previous reports, our study revealed a predominance of HLA-DRB1*03 and *04, as well as HLA-DQB1*02 and *03, in patients with T1D, with a non-significant trend suggesting a higher effect for the HLA-DRB1*04 allele peaking among children aged 1–5 years. The gene discussed is HLA-DRB1; the disease is type 1 diabetes mellitus.