Analysis on datasets from Cancer Genome Atlas (TCGA) of the expression of LDLR and HMGCR in ovarian cancer patients, as well as a retrospective study on 65 patients found that patients with a high expression of LDLR and low expression of HMGCR in their tumors, had a poorer disease-free survival, as well as a poorer overall survival, compared to patients with a low LDLR expression [115]. The gene discussed is LDLR; the disease is ovarian carcinoma.