The frequencies of cGAShigh, STINGhigh, and cGAShigh/STINGhigh GCs were higher in dMMR GC compared to pMMR/EBV (−) GC (Fig. 1C, D), suggesting that the tumor cell-intrinsic expression of cGAS–STING is up-regulated in dMMR GC. Here, STING1 is linked to neoplasm.