Consistent with our observations in the induced TiRP model (Fig. 1c), the transfer of PHD2/3 KO OVA-specific OT-1 T cells resulted in a robust and effective anti-tumor response in the ovalbumin-expressing MC38 (MC38-OVA) model (Fig. 4a–c), in which activated WT OT-1 CD8 T cells failed to inhibit tumor growth (Fig. 4b). The gene discussed is OXT; the disease is neoplasm.