In addition, in line with findings reported by Liikanen et al, a higher proportion of CD69pos CD103pos OT-1 CD8 T cells was found in tumors of mice treated with PHD2/3 KO OT-1 CD8 T cells (Fig. 5e), indicating an increase of tumor resident memory (Trm) subset of CD8 T cells19. This evidence concerns the gene CD8A and neoplasm.