We found that MIP-1α and TNF-α in the model group were consistently higher than those in the NS group at the same stage, and the content of both decreased gradually with time, which is consistent with the pathological features of the BLM-induced PF model; Encouragingly, Gen significantly reduced the levels of MIP-1α and TNF-α in BALF, suggesting that Gen is resistant to inflammatory responses during pulmonary fibrosis, which was also confirmed in pathological examinations. The gene discussed is TNF; the disease is pemphigus foliaceus.