Insulin resistance: 27.0%; carbohydrate metabolism disorders: 19.2% (impaired glucose tolerance: 15.4%, type 2 diabetes mellitus: 3.8%); metabolic syndrome: 3.8%; highest mean fasting insulin and HOMA-IR in subjects with SV and highest fasting and 2-hour postload glucose in subjects with NC (but no statistical comparisons were made). The gene discussed is INS; the disease is Impaired glucose tolerance.