Fasting glucose and HbA1c within the reference range in all patients with CAH; median fasting insulin: 11.0 mU/L, median HOMA-IR: 2.64; HOMA-IR > 90th percentile in 29.6% of patients; correlations between HOMA-IR and daily hydrocortisone dose, renin, and BMI SDS. The gene discussed is INS; the disease is congenital adrenal hyperplasia.