There was a significant difference between the three cohorts regarding CSF TF levels with the lowest levels in DLB GBA1 (398.0 pg/ml (±107.3)), followed by PD GBA1 (440.7 pg/ml (±137.8)) and CON (534.4 pg/ml (±161.6)) (p = 0.034). This evidence concerns the gene GBA1 and Parkinson disease.