Malaria‐infected children had relatively higher TNF‐α (p < .001), IFN‐ɣ (p < .001), IL‐1β (p < .001), IL‐6 (p < .001), GM‐CSF (p < .001), and IL‐10 (p < .001) levels than uninfected participants. This evidence concerns the gene TNF and malaria.