ITGA6 can regulate the expression of FGFR1 in glioblastoma stem cells through the ZEB1/YAP1 transcription complex and upregulate the proliferation and stemness of GBMSCs by synergistically interacting with FGFR1 (Kowalski-Chauvel et al., 2019). The gene discussed is FGFR1; the disease is glioblastoma.