MiR-197 has been shown to regulate the expression of ITGAV via the STAT5 pathway, thereby affecting the proliferation, invasion, and metastasis of prostate cancer cells, while miR-197 can also inhibit the growth of prostate cancer by targeting ITGAV and regulating the development of PCSCs through the STAT5 pathway (Ju et al., 2021). Here, ITGAV is linked to Familial prostate cancer.