As depicted in Table S8, genetically determined higher circulating GP73 concentration was associated with an increased risk of myocardial infarction (OR, 1.18; 95% CI, 1.09-1.28; P-value, <0.001), large artery atherosclerotic stroke (OR, 1.29; 95% CI, 1.07-1.55; P-value, 0.008) and PAD (OR, 1.001; 95% CI, 1.000-1.001; P-value, 0.02). The gene discussed is GOLM1; the disease is peripheral arterial disease.