Molecular upstream and downstream regulatory analysis of PTGS2 revealed its close biological association with pathways such as Positive regulation of nitrogen compound metabolic process (GO:0051173), Positive regulation of metabolic process (GO:0009893), and Regulation of catabolic process (GO:0009894), suggesting its potential role as a regulator in TAURINE METABOLISM involved in adventitial pathology of abdominal aortic aneurysms (Figure 8B). This evidence concerns the gene PTGS2 and abdominal aortic aneurysm.