Subsequently, based on gene expression and Cox risk analysis, we found that FAP expression was significantly up-regulated in the majority (73%) of cancers (Wilcoxon test, P < 0.05), and DAB2 expression was significantly up-regulated in nearly half of cancers (41%), that high expression of both genes usually predicted poorer OS of the patients (Figure 6C & 6D, Figure S12D-S12F). The gene discussed is DAB2; the disease is cancer.