In addition to GATA, MEF2 and NFAT families, other transcription factors, such as UBF1 86, ATF3 87, T-Cdk9 88, XBP1 89, MITF 90, HSF1 91, C/EBP 92, KLF11 93 and KLF5/BTEB2 94 have been implicated in regulating cardiac hypertrophy. This evidence concerns the gene XBP1 and cardiac hypertrophy.