In relative to HC, patients with PD showed remarkably reduced FC between ANG and PUT, and between ANG and PAL (FC of ANG.L-PUT.R: P = 0.020; FC of ANG.L-PAL.L: P = 0.036; FC of ANG.L-PAL.R: P = 0.027; FC of ANG.R- PUT.L: P = 0.00082) (Figure 4D). This evidence concerns the gene ANG and Parkinson disease.