Positive indicators in non-albumin proteins are often low molecular weight proteins: β2-microglobulin (26), α1-microglobulin, and retinol-binding proteins (27, 28), which, in combination with the above studies, suggests that non-albumin proteuric changes in the urine tests in the current Mendelian randomization may have a protective effect on the development of oral leukoplakia. This evidence concerns the gene ALB and Oral leukoplakia.