Peanut allergy prevalence in the USA has been estimated to range from 0.6% to as high as 2% of the population. Prevalence in France, Germany, Israel, Sweden, and the United Kingdom varies between 0.06% and 5.9%. Peanut allergy is an IgE-mediated type 1 hypersensitivity reaction. Tree nuts and peanuts account for 70-90% of food-related anaphylactic fatalities. This evidence concerns the gene IGHE and peanut allergic reaction.