Additionally, adults with human homeostatic iron regulator protein (HFE)-associated hereditary hemochromatosis often experience cardiac (dilated cardiomyopathy, pericarditis), hepatic (chronic hepatitis, fibrosis, cirrhosis), and endocrine gland (diabetes mellitus, hypoparathyroidism, hypothyroidism, hypopituitarism, adrenal insufficiency) complications14. This evidence concerns the gene HFE and Adrenal insufficiency.