INS and cancer: KEGG pathway analysis revealed that the differently methylated genes were significantly associated with 13 different pathways including ABC transporters, Gastric acid secretion, Bile secretion, Choline metabolism in cancer, Pancreatic secretion, Insulin resistance, Vitamin digestion, and absorption, Glutamatergic synapse, Synaptic vesicle cycle, GABAergic synapse, Salivary secretion, Inflammatory mediator regulation of TRP channels and Mineral absorption.