In fact, some viruses may induce a nonspecific immune activation and via similarities between viral peptides and self-peptides of skin membrane, leading to an immune response against self-antigens [9]. These autoantibodies react against epidermic basal membrane antigens (BP-180 or BP-230, a component of hemidesmosomes) and cause tissue damage. Potential triggering by COVID-19 has already been reported [10]. This evidence concerns the gene COL17A1 and COVID-19.