APOB and diabetes mellitus: We found that compared with patients with MCS, patients with FCS had (1) lower BMI; (2) younger age at assessment and earlier symptom onset; (3) higher likelihood of non-European ancestry; (4) higher TG levels at all stages, including greater proportions of those with TG that were never <10 mmol/L or <2 mmol/L; (5) higher baseline ratio of TG to TC, as well as lower apo B and HDL-C levels; (6) higher prevalence of episodes of acute pancreatitis; and (7) lower prevalence of secondary factors such as alcohol use and diabetes.