IGKV1D-22 and congenital non-bullous ichthyosiform erythroderma: This direction of change is in line with a positive correlation between S100A8/A9-positive cells with the severity of MΦ and neutrophil infiltration in the ileum of dogs with CIE [10] and could be explained by calprotectin being expressed by predominantly macrophages and neutrophils [9].