Literature on APP levels in endometritis [88–90], urinary tract infections [83], hoof and leg disorders [91–93], foot and mouth disease [94, 95], paratuberculosis [96, 97], bovine viral disease [98], infections with L. interrogans [62], bovine besnoitiosis [71], Babesia bigemina [99], respiratory disease [100], subclinical and clinical ketosis [101], traumatic reticuloperitonitis [102], peritonitis [103] and calf diarrhoea [104] was found and summarized in Table 10. The gene discussed is APP; the disease is viral infectious disease.