We performed ssGSEA analysis to quantify the level of infiltration of different immune cells in the tumor microenvironment and found that the level of infiltration of most immune cells was down-regulated in high HDAC10 group compared to the low HDAC10 group among 24 immune cell types, including B cells, dendritic cell (DC), eosinophils cells, immature DC (iDC) cells, macrophages, mast cells, T gamma delta (Tgd) cells, Th1 cells, Th17 cells, Th2 cells (Fig. 7A). This evidence concerns the gene HDAC10 and neoplasm.